Hier finden Sie eine Auswahl an Publikationen zu Tumoren im Kopf- und Halsbereich, die durch die mitwirkenden Kliniken des Kopf-Hals-Tumorzentrums veröffentlicht wurden.

Publikationen 2016

  • Elicin O, Nisa L, Dal Pra A, Bojaxhiu B, Caversaccio M, Schmücking M, Aebersold DM, Giger R. Up-front neck dissection followed by definitive (chemo)-radiotherapy in head and neck squamous cell carcinoma: Rationale, complications, toxicity rates, and oncological outcomes - A systematic review. Radiother Oncol. 2016 May;119(2):185-93. Pubmed
  • Giger R. Head and neck cancer: update and innovations. Rev Med Suisse. 2016 Jan 27;12(503):188-91. Pubmed
  • Elicin O, Albrecht T, Haynes AG, Bojaxhiu B, Nisa L, Caversaccio M, Dal Pra A, Schmücking M, Aebersold DM, Giger R. Outcomes in Advanced Head and Neck Cancer Treated with Up-front Neck Dissection prior to (Chemo)Radiotherapy. Otolaryngol Head Neck Surg. 2016 Feb;154(2):300-8. Pubmed
  • Anschütz L, Nisa L, Elicin O, Bojaxhiu B, Caversaccio M, Giger R. Pectoralis major myofascial interposition flap prevents postoperative pharyngocutaneous fistula in salvage total laryngectomy. Eur Arch Otorhinolaryngol. 2016 Nov;273(11):3943-3949. Pubmed
  • Medina J, Zbären P, Bradley PJ. Management of Regional Metastases of Malignant Salivary Gland Neoplasms. Adv Otorhinolaryngol. 2016;78:132-40. Pubmed
  • Borner U, Stow NW, Landis BN. Pleomorphic Adenoma of the Parotid Gland. Am J Med. 2016 Jan;129(1):e1-2. Pubmed
  • Cacicedo J, Navarro A, Del Hoyo O, Gomez-Iturriaga A, Alongi F, Medina JA, Elicin O, Skanjeti A, Giammarile F, Bilbao P, Casquero F, de Bari B, Dal Pra A. Role of fluorine-18 fluorodeoxyglucose PET/CT in head and neck oncology: the point of view of the radiation oncologist. Br J Radiol. 2016 Nov;89(1067):20160217. Pubmed
  • Elicin O, Ozsahin M. Current Role of Dacomitinib in Head and Neck Cancer. Expert Opin Investig Drugs. 2016 Jun;25(6):735-42. Pubmed
  • Elicin O, Schmucking M, Bromme J, Rauch D, Ambarcioglu P, Plasswilm L, Geretschlager A, Ghadjar P, Giger R, Aebersold DM. Volumetric regression ratio of the primary tumor and metastatic lymph nodes after induction chemotherapy predicts overall survival in head and neck squamous cell carcinoma: a retrospective analysis. J BUON. 2016 Jan-Feb;21(1):175-81. Pubmed
  • Merki V, Pichler J, Giger R, Mantokoudis G. Chylothorax in thyroid surgery: a very rare case and systematic review of the literature. J Otolaryngol Head Neck Surg. 2016 Oct 18;45(1):52. Pubmed
  • Landis BN, Borner U. Neurofibromatosis of the tongue. Med J Aust. 2016 Oct 3;205(7):300. Pubmed
  • Mattioli F, Presutti L, Caversaccio M, Bonali M, Anschuetz L. Novel Dissection Station for Endolaryngeal Microsurgery and Laser Surgery: Development and Dissection Course Experience. Otolaryngol Head Neck Surg. 2016 Sep 6. [Epub ahead of print] Pubmed
  • Suter VG, Negoias S, Friedrich H, Landis BN, Caversaccio MD, Bornstein MM. Gustatory function and taste perception in patients with oral lichen planus and tongue involvement. Clin Oral Investig. Clin Oral Investig. 2017 Apr;21(3):957-964. Pubmed
  • Stieger C, Arnold A, Kruse A, Wiedmer S, Widmer M, Guignard J, Schutz D, Guenat JM, Bachtler M, Caversaccio M, Uehlinger DE, Frey FJ, Hausler R. Novel Bone-Anchored Vascular Access on the Mastoid for Hemodialysis: Concept and Preclinical Trials. IEEE Trans Biomed Eng. 2016 May;63(5):984-990. Pubmed

Publikationen 2015

  • Geretschläger A, Bojaxhiu B, Dal Pra A, Leiser D, Schmücking M, Arnold A, Ghadjar P, Aebersold DM. Definitive intensity modulated radiotherapy in locally advanced hypopharygeal and laryngeal squamous cell carcinoma: mature treatment results and patterns of locoregional failure. Radiat Oncol. 2015 Jan 17;10:20. Pubmed
  • Nisa L, Aebersold DM, Giger R, Caversaccio MD, Borner U, Medová M, Zimmer Y., Profiling invasiveness in head and neck cancer: recent contributions of genomic and transcriptomic approaches. Cancers (Basel). 2015 Mar 31;7(2):585-97.  Pubmed
  • Nisa L, Landis BN, Salmina C, Ailianou A, Karamitopoulou E, Giger R., Warthin's tumor of the larynx: a very rare case and systematic review of the literature. J Otolaryngol Head Neck Surg. 2015 May 12;44:16. Pubmed
  • Nisa L, Salmina C, Dettmer MS, Arnold A, Aebersold DM, Borner U, Giger R., Implications of intraglandular lymph node metastases in primary carcinomas of the parotid gland. Laryngoscope. 2015 Sep;125(9):2099-106. Pubmed
  • Witt RL, Eisele DW, Morton RP, Nicolai P, Poorten VV, Zbären P. Etiology and management of recurrent parotid pleomorphic adenoma. Laryngoscope. 2015 Apr;125(4):888-93. Pubmed
  • Mikami K, Medová M, Nisa L, Francica P, Glück AA, Tschan MP, Blaukat A, Bladt F, Aebersold DM, Zimmer Y. Impact of p53 Status on Radiosensitization of Tumor Cells by MET Inhibition-Associated Checkpoint Abrogation. Mol Cancer Res. 2015 Dec;13(12):1544-53. Pubmed
  • Leiser D, Medová M, Mikami K, Nisa L, Stroka D, Blaukat A, Bladt F, Aebersold DM, Zimmer Y. KRAS and HRAS mutations confer resistance to MET targeting in preclinical models of MET-expressing tumor cells. Mol Oncol. 2015 Aug;9(7):1434-46. Pubmed

Publikationen 2017

Publikationen 2017

Impact of human papillomavirus on outcome in patients with oropharyngeal cancer treated with primary surgery.

Broglie MA, Stoeckli SJ, Sauter R, Pasche P, Reinhard A, de Leval L, Huber GF, Pezier TF, Soltermann A, Giger R, Arnold A, Dettmer M, Arnoux A, Müller M, Spreitzer S, Lang F, Lutchmaya M, Stauffer E, Espeli V, Martucci F, Bongiovanni M, Foerbs D, Jochum W.

Head Neck. 2017 Oct;39(10):2004-2015. doi: 10.1002/hed.24865. Epub 2017 Jul 10.

PMID: 28691255


PIK3CA hotspot mutations differentially impact responses to MET targeting in MET-driven and non-driven preclinical cancer models.

Nisa L, Häfliger P, Poliaková M, Giger R, Francica P, Aebersold DM, Charles RP, Zimmer Y, Medová M.

Mol Cancer. 2017 May 22;16(1):93. doi: 10.1186/s12943-017-0660-5.

PMID: 28532501


18F-FDG PET/CT of Papillary Carcinoma in a Lateral Thyroglossal Duct Cyst.

Sachpekidis C, Dettmer MS, Weidner S, Giger R, Wartenberg J.

Clin Nucl Med. 2017 Aug;42(8):e371-e374. doi: 10.1097/RLU.0000000000001712.

PMID: 28525461


T1-2 glottic cancer treated with radiotherapy and/or surgery.

Shelan M, Anschuetz L, Schubert AD, Bojaxhiu B, Dal Pra A, Behrensmeier F, Aebersold DM, Giger R, Elicin O.

Strahlenther Onkol. 2017 Dec;193(12):995-1004. doi: 10.1007/s00066-017-1139-4. Epub 2017 May 4.

PMID: 28474090


NSD1- and NSD2-damaging mutations define a subset of laryngeal tumors with favorable prognosis.

Peri S, Izumchenko E, Schubert AD, Slifker MJ, Ruth K, Serebriiskii IG, Guo T, Burtness BA, Mehra R, Ross EA, Sidransky D, Golemis EA.

Nat Commun. 2017 Nov 24;8(1):1772. doi: 10.1038/s41467-017-01877-7.

PMID: 29176703


Clinical evaluation of the iterative metal artefact reduction algorithm for post-operative CT examination after maxillofacial surgery.

Hakim A, Slotboom J, Lieger O, Schlittler F, Giger R, Michel C, Wiest R, Wagner F.

Dentomaxillofac Radiol. 2017 Apr;46(4):20160355. doi: 10.1259/dmfr.20160355. Epub 2017 Mar 7.

PMID: 28112538


Primary tumor volume delineation in head and neck cancer: missing the tip of the iceberg?

Elicin O, Terribilini D, Shelan M, Volken W, Mathier E, Dal Pra A, Aebersold DM, Fix MK, Manser P.

Radiat Oncol. 2017 Jun 20;12(1):102. doi: 10.1186/s13014-017-0838-4.

PMID: 28633674


The latest prospects of investigational drugs for head and neck cancer.

Elicin O, Ozsahin M.

Expert Opin Investig Drugs. 2017 Mar;26(3):265-268. doi: 10.1080/13543784.2017.1279145. Epub 2017 Jan 10. No abstract available.

PMID: 28056562



Bilateral lingual artery stenosis: A rare, late complication of chemoradiotherapy.

Holtz F, Monnier Y, Borner U, Nisa L.

Eur Ann Otorhinolaryngol Head Neck Dis. 2017 Sep;134(4):269-271. doi: 10.1016/j.anorl.2017.02.002. Epub 2017 Mar 11.

PMID: 28291634

Publikationen 2018

Publikationen 2018

Comparison of contemporary staging systems for oropharynx cancer in a surgically treated multi-institutional cohort.

Elicin O, Broglie MA, Fankhauser N, Stoeckli SJ, Pasche P, Reinhard A, Bongiovanni M, Huber GF, Morand GB, Soltermann A, Arnold A, Dettmer MS, Arnoux A, Stauffer E, Espeli V, Martucci F, Aebersold DM, Giger R.

Head Neck. 2019 May;41(5):1395-1402. doi: 10.1002/hed.25574. Epub 2018 Dec 28.

PMID: 30593685


Incidence of second primary cancers after radiotherapy combined with platinum and/or cetuximab in head and neck cancer patients.

Elicin O, Sermaxhaj B, Bojaxhiu B, Shelan M, Giger R, Rauch D, Aebersold DM.

Strahlenther Onkol. 2019 Jun;195(6):468-474. doi: 10.1007/s00066-018-1400-5. Epub 2018 Nov 21.

PMID: 30465265


Relation of baseline neutrophil-to-lymphocyte ratio to survival and toxicity in head and neck cancer patients treated with (chemo-) radiation.

Bojaxhiu B, Templeton AJ, Elicin O, Shelan M, Zaugg K, Walser M, Giger R, Aebersold DM, Dal Pra A.

Radiat Oncol. 2018 Nov 6;13(1):216. doi: 10.1186/s13014-018-1159-y.

PMID: 30400969


Risk analysis for tracheostomy dependency in curatively treated laryngeal cancer with organ preservation.

Anschuetz L, Visini M, Shelan M, Elicin O, Giger R.

Head Neck. 2018 Nov;40(11):2469-2475. doi: 10.1002/hed.25373. Epub 2018 Oct 11.

PMID: 30307670


Comprehensive Genomic Profiling of Patient-matched Head and Neck Cancer Cells: A Preclinical Pipeline for Metastatic and Recurrent Disease.

Nisa L, Barras D, Medová M, Aebersold DM, Medo M, Poliaková M, Koch J, Bojaxhiu B, Eliçin O, Dettmer MS, Angelino P, Giger R, Borner U, Caversaccio MD, Carey TE, Ho L, McKee TA, Delorenzi M, Zimmer Y.

Mol Cancer Res. 2018 Dec;16(12):1912-1926. doi: 10.1158/1541-7786.MCR-18-0056. Epub 2018 Aug 14.

PMID: 30108165


Effect of preoperative immunonutrition on postoperative short-term outcomes of patients with head and neck squamous cell carcinoma.

Aeberhard C, Mayer C, Meyer S, Mueller SA, Schuetz P, Stanga Z, Giger R.

Head Neck. 2018 May;40(5):1057-1067. doi: 10.1002/hed.25072. Epub 2018 Jan 24.

PMID: 29368455


Letter to the Editor on Nevens et al.

Elicin O, Giger R.

Radiother Oncol. 2018 Mar;126(3):570. doi: 10.1016/j.radonc.2017.12.016. Epub 2018 Jan 6. No abstract available.

PMID: 29317113


Salvage-Chirurgie bei Tumorrezidiven der Mundhöhle – Einfluss der vorherigen Behandlung und des Patientenalters – Letter to the editor.

Giger R, Elicin O.

Laryngorhinootologie. 2018 Jan;97(1):8-10. doi: 10.1055/s-0043-121838. Epub 2018 Jan 4. German.

PMID: 29301156


Recurrent parotid gland carcinoma: how effective is salvage surgery?

Nisa L, Borner U, Dür C, Arnold A, Giger R.

Eur Arch Otorhinolaryngol. 2018 Feb;275(2):507-513. doi: 10.1007/s00405-017-4829-8. Epub 2017 Dec 1.

PMID: 29196807


Treatment of tracheoesophageal fistula after laryngectomy by a customized tracheal prosthesis.

Mueller SA, Dehnbostel S, Dehnbostel F, Giger R.

Laryngoscope. 2018 Aug;128(8):1858-1861. doi: 10.1002/lary.27027. Epub 2017 Nov 29. No abstract available.

PMID: 29193191


Part 1: Optimization and evaluation of dynamic trajectory radiotherapy.

Fix MK, Frei D, Volken W, Terribilini D, Mueller S, Elicin O, Hemmatazad H, Aebersold DM, Manser P.

Med Phys. 2018 Jul 10. doi: 10.1002/mp.13086. [Epub ahead of print]

PMID: 29992587


Identification of a MET-eIF4G1 translational regulation axis that controls HIF-1α levels under hypoxia.

Glück AA, Orlando E, Leiser D, Poliaková M, Nisa L, Quintin A, Gavini J, Stroka DM, Berezowska S, Bubendorf L, Blaukat A, Aebersold DM, Medová M, Zimmer Y.

Oncogene. 2018 Jul;37(30):4181-4196. doi: 10.1038/s41388-018-0256-6. Epub 2018 May 2.

PMID: 29717265


MEK Inhibition Induces Therapeutic Iodine Uptake in a Murine Model of Anaplastic Thyroid Cancer.

ElMokh O, Taelman V, Radojewski P, Roelli MA, Stoss A, Dumont RA, Dettmer MS, Phillips WA, Walter MA, Charles RP.

J Nucl Med. 2019 Jul;60(7):917-923. doi: 10.2967/jnumed.118.216721. Epub 2018 Nov 21.

PMID: 30464041